SLAY THE SPIRE / POTIONS
Potions
Emergency damage, defense, debuff and draw resources.
15 entries · Reviewed 2026-10-28
VOLPEDIA ORIGINAL GAME ENCYCLOPEDIA
Potions reference library
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15 of 15 entries · Original Slay the Spire 1
Potions · REFERENCE
Fire Potion
Deals a fixed burst of damage to an enemy and can bypass a bad hand.
Potions · REFERENCE
Block Potion
Supplies immediate Block in a turn with insufficient defensive cards.
Potions · REFERENCE
Strength Potion
Grants temporary Strength for the encounter.
Potions · REFERENCE
Dexterity Potion
Increases Block gained from compatible cards for the encounter.
Potions · REFERENCE
Energy Potion
Supplies extra energy on the chosen turn.
Potions · REFERENCE
Swift Potion
Draws additional cards during combat.
Potions · REFERENCE
Fear Potion
Applies Vulnerable to an enemy to amplify following attack damage.
Potions · REFERENCE
Weak Potion
Applies Weak to an enemy to reduce attack damage.
Potions · REFERENCE
Explosive Potion
Deals damage to every enemy, offering emergency area clear.
Potions · REFERENCE
Poison Potion
Applies Poison to one enemy, enabling damage over subsequent turns.
Potions · REFERENCE
Duplication Potion
Allows an upcoming card play to be duplicated.
Potions · REFERENCE
Artifact Potion
Applies Artifact to block a future debuff.
Potions · REFERENCE
Entropic Brew
Fills empty potion slots with random potions.
Potions · REFERENCE
Fairy in a Bottle
Revives the character from lethal HP loss once while kept in the potion slot.
Potions · REFERENCE
Ghost in a Jar
Gives Intangible for one turn, a uniquely strong defensive tool.
Independent Volpedia editorial resource, not affiliated with Mega Crit. Original game (Slay the Spire 1), reviewed 2026-10-28. Slay the Spire 2 has separate rules, cards and characters and is not included here. Category graphics are original conceptual illustrations, not game screenshots or actual card artwork. Detailed numerical card costs, damage, upgrade effects and drop percentages are omitted where not individually checked. Editorial verification records are stored separately from public articles.