SLAY THE SPIRE / BOSSES
Bosses
All ten Act I–IV bosses, patterns, positioning and counterplay.
10 entries · Reviewed 2026-10-28
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Bosses reference library
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10 of 10 entries · Original Slay the Spire 1
Bosses · REFERENCE
The Guardian
Act I boss that changes combat stances as damage thresholds are reached.
Bosses · REFERENCE
Hexaghost
Act I boss whose opening pattern and later multi-hits test reliable defense and scaling.
Bosses · REFERENCE
Slime Boss
Act I boss whose split can create a major shift in enemy count and immediate pressure.
Bosses · REFERENCE
Bronze Automaton
Act II boss that summons minions and threatens an extremely powerful Hyper Beam.
Bosses · REFERENCE
The Collector
Act II boss relying on summons and recurring buffs and debuffs.
Bosses · REFERENCE
The Champ
Act II boss with a dangerous phase transition and large burst sequences.
Bosses · REFERENCE
Awakened One
Act III boss whose scaling punishes careless Power plays and includes a second phase.
Bosses · REFERENCE
Time Eater
Act III boss who limits how many cards can be played across turns.
Bosses · REFERENCE
Donu and Deca
Act III paired boss where repeated buffs and attacks demand target priority.
Bosses · REFERENCE
Corrupt Heart
Optional final boss of Act IV, gated behind gathering three colored keys.
Independent Volpedia editorial resource, not affiliated with Mega Crit. Original game (Slay the Spire 1), reviewed 2026-10-28. Slay the Spire 2 has separate rules, cards and characters and is not included here. Category graphics are original conceptual illustrations, not game screenshots or actual card artwork. Detailed numerical card costs, damage, upgrade effects and drop percentages are omitted where not individually checked. Editorial verification records are stored separately from public articles.