What is Buffer?
Negates a future HP-loss instance, useful against large hits.
This reference covers gameplay decisions in the original Slay the Spire. Character-specific options and relic synergy can change how useful an item is, so consider your current deck, health, upcoming enemy and available resources before applying a strategy.
When and how to use it
Save it for predictable heavy attacks, accounting for multi-hits and small chip damage.
What to avoid
A tiny first hit may consume Buffer before the major attack.