What is Fiend Fire?
Exhausts other cards in hand to deal repeated damage, trading deck resources for burst.
This reference covers gameplay decisions in the original Slay the Spire. Character-specific options and relic synergy can change how useful an item is, so consider your current deck, health, upcoming enemy and available resources before applying a strategy.
When and how to use it
Sequence draw and hand composition to maximize payoff and avoid consuming essential future answers.
What to avoid
Do not burn your remaining scaling or defensive pieces for nonlethal damage.