Act III elite that alternates between more and less vulnerable turns and adds Burns.
QUICK REFERENCESlay the Spire 1Reviewed 2026-10-28Reference / noindex
OVERVIEW
What is Nemesis?
Act III elite that alternates between more and less vulnerable turns and adds Burns.
This reference covers gameplay decisions in the original Slay the Spire. Character-specific options and relic synergy can change how useful an item is, so consider your current deck, health, upcoming enemy and available resources before applying a strategy.
PRACTICAL STRATEGY
When and how to use it
Hold burst for a vulnerable phase and retain reliable defenses.
COMMON MISTAKES
What to avoid
Using your biggest attack during Intangible wastes it.
Independent Volpedia editorial resource, not affiliated with Mega Crit. Original game (Slay the Spire 1), reviewed 2026-10-28. Slay the Spire 2 has separate rules, cards and characters and is not included here. Category graphics are original conceptual illustrations, not game screenshots or actual card artwork. Detailed numerical card costs, damage, upgrade effects and drop percentages are omitted where not individually checked. Editorial verification records are stored separately from public articles.