SLAY THE SPIRE / ENEMIES

Louse

Early enemy that can use Curl Up and varied intents.

QUICK REFERENCESlay the Spire 1Reviewed 2026-10-28Reference / noindex

OVERVIEW

What is Louse?

Early enemy that can use Curl Up and varied intents.

This reference covers gameplay decisions in the original Slay the Spire. Character-specific options and relic synergy can change how useful an item is, so consider your current deck, health, upcoming enemy and available resources before applying a strategy.

PRACTICAL STRATEGY

When and how to use it

Anticipate its defensive reaction when calculating lethal.

COMMON MISTAKES

What to avoid

Misreading a status/buff turn can waste damage or defense.

CONTINUE ON VOLPEDIA

Related topics and walkthroughs

Act II flying enemy that can be grounded by repeated hits.

Act II foe whose Hex debuff creates Dazed cards as you use Skills.

Early enemy that gains recurring Strength after setup.

ENEMIESJaw Worm

Early enemy whose attacks and buffs demand basic defensive sequencing.

Act II enemy with dangerous attacks and disruptive debuffs.

ENEMIESSnake Plant

Act II enemy with repeated multi-hit attacks and defensive scaling.

Act II foe whose confusion effect changes card costs.

Back to Enemies

Independent Volpedia editorial resource, not affiliated with Mega Crit. Original game (Slay the Spire 1), reviewed 2026-10-28. Slay the Spire 2 has separate rules, cards and characters and is not included here. Category graphics are original conceptual illustrations, not game screenshots or actual card artwork. Detailed numerical card costs, damage, upgrade effects and drop percentages are omitted where not individually checked. Editorial verification records are stored separately from public articles.